GENETIC AND IMMUNOLOGICAL PHENOTYPES OF REACTIVE ARTHRITIS: A PERSONALIZED DIAGNOSTIC MODEL
Keywords:
asymmetric oligoarthritis, enthesitis, axial involvement, and extra-articular manifestations affecting the eyes, skin, and mucosal surfacesAbstract
Reactive arthritis (ReA) is an inflammatory joint disease that develops as a sterile immune-mediated response following certain genitourinary or gastrointestinal infections. Unlike septic arthritis, reactive arthritis is characterized by the absence of viable pathogens within the affected joints, underscoring its immunopathological rather than infectious nature. Clinically, ReA is often associated with asymmetric oligoarthritis, enthesitis, axial involvement, and extra-articular manifestations affecting the eyes, skin, and mucosal surfaces. Despite its well-recognized clinical spectrum, reactive arthritis remains a diagnostically challenging condition due to its heterogeneous presentation and variable disease course.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
